4, January 2022
France detects new Covid variant IHU, 12 infected 0
As the world grapples with the highly mutated Omicron variant of SARS-CoV-2, scientists have identified a new strain of the Covid-19 causing virus in Southern France.
Known as ‘IHU’, the B.1.640.2 variant has been reported by researchers at institute IHU Mediterranee Infection in at least 12 cases, and has been linked to travel to African country Cameroon.
However, the researchers noted that it is too early to speculate on how this variant behaves as far as infection and protection from vaccines is concerned.
The yet-to-be peer-reviewed study, posted on the preprint repository MedRxiv on December 29, revealed that IHU has 46 mutations and 37 deletions resulting in 30 amino acid substitutions and 12 deletions.
Amino acids are molecules that combine to form proteins, and both are the building blocks of life.
Fourteen amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein.
Most currently used vaccines are targeted at the spike protein of SARS-CoV-2, which the virus uses to enter and infect the cells.
N501Y and E484K mutations were earlier also found in Beta, Gamma, Theta and Omicron variants.
“The mutation set and phylogenetic position of the genomes obtained here indicate based on our previous definition a new variant we named IHU,” the authors of the study said.
“These data are another example of the unpredictability of the emergence of SARS-CoV-2 variants, and of their introduction in a given geographical area from abroad,” they added.
The B.1.640.2 has not been identified in other countries so far or labelled a variant under investigation by the World Health Organization (WHO).
According to the researchers, the index (first) case was an adult diagnosed positive by RTPCR performed in a laboratory on a nasopharyngeal sample collected in mid-November last year.
Epidemiologist Eric Feigl-Ding posted a long Twitter thread in which he said that new variants keep emerging but it does not necessarily mean they will be more dangerous.
“What makes a variant more well-known and dangerous is its ability to multiply because of the number of mutations it has in relation to the original virus,” Feigl-Ding tweeted on Tuesday.
“This is when it becomes a “variant of concern” – like Omicron, which is more contagious and more past immunity evasive. It remains to be seen in which category this new variant will fall,” he said.
Many countries are currently experiencing a spike in Covid-19 cases driven by the Omicron variant which was first identified in South Africa and Botswana in November last year.
Since then, the variant of concern has spread to over 100 countries.
In India, a total of 1,892 cases of Omicron variant have been detected across 23 states and Union Territories so far.
Source: Times of India



















23, January 2022
Africa Cup of Nations: Comoros struggle to put team together against Cameroon as Covid racks squad 0
The Comoros, the surprise package of the Africa Cup of Nations, are struggling to put a team together for their last-16 tie against host nation Cameroon after 12 players and management tested postive for Covid-19, their federation announced Saturday.
The 12 positive tests include both of the Coelacanths’ fit goalkeepers, with the third goalkeeper, Salim Ben Boina already injured. Comoros are due to face Cameroon on Monday.
“The Coelacanths affected by Covid…include coach Amir Abdou, our only two goalkeepers, Moyadh Ousseini and Ali Ahamada,” the federation tweeted two days before an historic match for the Comoros who qualified for the last 16 in their first appearance at the tournament.
In a video posted on the account, general manager El Hadad Hamidi also named five outfield players who have tested positive: midfielders Nakibou Aboubakari, Yacine Bourhane, striker Mohamed M’Changama and defenders Kassim Abdallah and Alexis Souahy.
With no goalkeepers currently available for the tie, the Comoros are in serious trouble.
Confederation of African Football rules for the tournament dictate that teams must play games as long as at least 11 players test negative for the coronavirus.
If no goalkeeper is available, an outfield player has to stand in.
“We are trying to do everything in our power to find alternative solutions” but “without the coach, without major players and especially without our only two goalkeepers who remained, the situation is quite complicated”, admitted Hamidi.
The Comoros, representing a tiny island nation off the south-east coast of Africa, snatched their qualification to everyone’s surprise by beating Ghana 3-2 and advancing as one of the best third-placed sides.
Source: AFP